{"id":13560,"date":"2026-03-11T17:11:54","date_gmt":"2026-03-11T08:11:54","guid":{"rendered":"https:\/\/miragen.clinic\/%e3%82%a2%e3%82%af%e3%83%aa%e3%83%bc%e3%83%95\/"},"modified":"2026-07-13T13:32:44","modified_gmt":"2026-07-13T04:32:44","slug":"%e3%82%a2%e3%82%af%e3%83%aa%e3%83%bc%e3%83%95","status":"publish","type":"page","link":"https:\/\/miragen.clinic\/ja\/%e3%82%a2%e3%82%af%e3%83%aa%e3%83%bc%e3%83%95\/","title":{"rendered":"\u30a2\u30af\u30ea\u30fc\u30d5"},"content":{"rendered":"\n<div class=\"wp-block-group has-custom-color-4-background-color has-background has-global-padding is-layout-constrained wp-container-core-group-is-layout-e96bc7c8 wp-block-group-is-layout-constrained\" style=\"padding-top:240px;padding-right:var(--wp--preset--spacing--superbspacing-small);padding-bottom:240px;padding-left:var(--wp--preset--spacing--superbspacing-small)\">\n<p class=\"has-custom-color-6-color has-text-color has-link-color wp-elements-0b6aa2df3fc85f9ce20be537421f0c05 wp-block-paragraph\">\u85ac\u5264\u6848\u5185<\/p>\n\n\n\n<h1 class=\"wp-block-heading has-text-align-left has-custom-color-1-color has-text-color has-link-color wp-elements-9547128bbb85000c8775db82fecb3d3f\">\u30a2\u30af\u30ea\u30fc\u30d5 | \u76ae\u819a\u30d0\u30ea\u30a2\u3068\u76ae\u8102\u3001\u4e8c\u514e\u3092\u8ffd\u3063\u3066\u4e8c\u514e\u3092\u5f97\u308b\u30af\u30ea\u30fc\u30e0<\/h1>\n<\/div>\n\n<div class=\"wp-block-group has-custom-color-2-background-color has-background has-global-padding is-layout-constrained wp-container-core-group-is-layout-1b17c90e wp-block-group-is-layout-constrained\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--superbspacing-xlarge);padding-right:var(--wp--preset--spacing--superbspacing-small);padding-bottom:var(--wp--preset--spacing--superbspacing-xlarge);padding-left:var(--wp--preset--spacing--superbspacing-small)\">\n<p class=\"wp-block-paragraph\">\u30a2\u30af\u30ea\u30fc\u30d5\u306f\u3001\u30cb\u30ad\u30d3\u6cbb\u7642\u306b\u4f7f\u7528\u3055\u308c\u308b\u5916\u7528\u30ec\u30c1\u30ce\u30a4\u30c9\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30cb\u30ad\u30d3\u3092\u4f34\u3046\u76ae\u819a\u708e\u306e\u60a3\u8005\u69d8\u306b\u5bfe\u3057\u3001\u30cb\u30ad\u30d3\u6cbb\u7642\u3060\u3051\u3067\u306a\u304f\u3001\u30ea\u30c3\u30c1\u306a\u4fdd\u6e7f\u5264\u306e\u4f7f\u7528\u3092\u53ef\u80fd\u306b\u3059\u308b\u305f\u3081\u306b\u51e6\u65b9\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-rank-math-toc-block has-custom-color-5-color has-custom-color-11-background-color has-text-color has-background has-link-color wp-elements-c3f54db22cf5c0264a7f29606ca4810f\" style=\"padding-top:var(--wp--preset--spacing--superbspacing-xsmall);padding-right:0;padding-bottom:var(--wp--preset--spacing--superbspacing-xsmall);padding-left:0\" id=\"rank-math-toc\"><h2>\u76ee\u6b21<\/h2><nav><ul><li class=\"\"><a href=\"#sec-1\">1. \u30a2\u30af\u30ea\u30fc\u30d5\u3068\u306f\uff1f<\/a><\/li><li class=\"\"><a href=\"#sec-2\">2. \u76ae\u819a\u708e\u306e\u60a3\u8005\u69d8\u306b\u30a2\u30af\u30ea\u30fc\u30d5\u3092\u4f7f\u7528\u3059\u308b\u7406\u7531<\/a><\/li><li class=\"\"><a href=\"#sec-3\">3. \u30cb\u30ad\u30d3\u304c\u3067\u304d\u308b\u904e\u7a0b<\/a><\/li><li class=\"\"><a href=\"#sec-4\">4. \u524d\u4e16\u4ee3\u3088\u308a\u3082\u523a\u6fc0\u304c\u5c11\u306a\u3044\u3067\u3059<\/a><\/li><li class=\"\"><a href=\"#sec-5\">5. \u7d4c\u53e3\u30ec\u30c1\u30ce\u30a4\u30c9\u3092\u5148\u306b\u4f7f\u3046\u7406\u7531<\/a><\/li><li class=\"\"><a href=\"#sec-6\">6. \u4f7f\u7528\u65b9\u6cd5<\/a><\/li><li class=\"\"><a href=\"#sec-7\">7. \u598a\u5a20\u30fb\u6388\u4e73<\/a><\/li><li class=\"\"><a href=\"#sec-8\">8. \u7d50\u8ad6<\/a><\/li><li class=\"\"><a href=\"#sec-faq\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 id=\"sec-1\" class=\"wp-block-heading\">1. \u30a2\u30af\u30ea\u30fc\u30d5\u3068\u306f\uff1f<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-color-5-color has-alpha-channel-opacity has-custom-color-5-background-color has-background is-style-wide\" style=\"margin-top:var(--wp--preset--spacing--superbspacing-xsmall);margin-bottom:var(--wp--preset--spacing--superbspacing-xsmall)\" \/>\n\n\n\n<p class=\"wp-block-paragraph\">\u30a2\u30af\u30ea\u30fc\u30d5\u306f\u3001\u30b9\u30c6\u30a3\u30fc\u30d0A\u3084\u30c8\u30a5\u30a8\u30f3\u30c6\u30a3\u30af\u30ea\u30fc\u30e0\uff08\u7b2c1\u4e16\u4ee3\uff09\u3001\u30c7\u30a3\u30d5\u30a7\u30ea\u30f3\uff08\u7b2c3\u4e16\u4ee3\uff09\u306b\u7d9a\u304f<strong>\u7b2c4\u4e16\u4ee3\u306e\u30ec\u30c1\u30ce\u30a4\u30c9\u8edf\u818f<\/strong>\u3067\u3059\u3002\u6210\u5206\u540d\u306f<strong>\u30c8\u30ea\u30d5\u30a1\u30ed\u30c6\u30f3\uff08Trifarotene\uff09<\/strong>\u3067\u3001\u76ae\u819a\u306b\u6700\u3082\u591a\u304f\u5206\u5e03\u3059\u308b<strong>RAR-\u03b3\u53d7\u5bb9\u4f53\u3068\u9078\u629e\u7684\u306b\u7d50\u5408<\/strong>\u3057\u307e\u3059\u3002<sup><a style=\"color:inherit\" href=\"#\ucc38\uace0\ubb38\ud5cc\">1<\/a><\/sup> <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30ec\u30c1\u30ce\u30a4\u30c9\u306f\u3001\u904e\u5270\u306a\u89d2\u8cea\u3068\u76ae\u8102\u304c\u6bdb\u7a74\u3092\u585e\u3050\u306e\u3092\u6291\u5236\u3059\u308b\u85ac\u5264\u3067\u3059\u3002\u307e\u305f\u3001\u9577\u671f\u4f7f\u7528\u6642\u306b\u306f<strong>\u76ae\u819a\u30d0\u30ea\u30a2\u3092\u3088\u308a\u5f37\u56fa\u306b<\/strong>\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<sup><a style=\"color:inherit\" href=\"#\ucc38\uace0\ubb38\ud5cc\">2<\/a><\/sup> <\/p>\n\n\n\n<figure class=\"wp-block-image alignwide size-large\"><img decoding=\"async\" width=\"1024\" height=\"572\" src=\"https:\/\/miragen.clinic\/wp-content\/uploads\/2026\/03\/aklief-cream-product-photo.png\" alt=\"\u7b2c4\u4e16\u4ee3\u30ec\u30c1\u30ce\u30a4\u30c9\u6210\u5206\u30c8\u30ea\u30d5\u30a1\u30ed\u30c6\u30f3\u3092\u542b\u6709\u3057\u305f\u30a2\u30af\u30ea\u30fc\u30d5\uff08Aklief\uff090.005%\u30af\u30ea\u30fc\u30e0\u30fb\u30dd\u30f3\u30d7\u578b\u5bb9\u5668\u306e\u5b9f\u7269\u88fd\u54c1\u5199\u771f\u3002\u30ac\u30eb\u30c7\u30eb\u30de\u793e\u88fd\u9020\u306e\u533b\u7642\u7528\u533b\u85ac\u54c1\u3002\" class=\"wp-image-8660\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 id=\"sec-2\" class=\"wp-block-heading\">2. \u76ae\u819a\u708e\u306e\u60a3\u8005\u69d8\u306b\u30a2\u30af\u30ea\u30fc\u30d5\u3092\u4f7f\u7528\u3059\u308b\u7406\u7531<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-color-5-color has-alpha-channel-opacity has-custom-color-5-background-color has-background is-style-wide\" style=\"margin-top:var(--wp--preset--spacing--superbspacing-xsmall);margin-bottom:var(--wp--preset--spacing--superbspacing-xsmall)\" \/>\n\n\n\n<p class=\"wp-block-paragraph\">\u30a2\u30c8\u30d4\u30fc\u30fb\u9152\u3055\u6027\u76ae\u819a\u708e\u30fb\u8102\u6f0f\u6027\u76ae\u819a\u708e\u306e\u6838\u5fc3\u306f<strong>\u76ae\u819a\u30d0\u30ea\u30a2\u306e\u640d\u50b7<\/strong>\u3067\u3059\u3002\u30d0\u30ea\u30a2\u304c\u5f31\u3044\u3068\u5916\u90e8\u523a\u6fc0\u306b\u5f31\u304f\u306a\u308b\u305f\u3081\u3001\u30ea\u30c3\u30c1\u306a\u30af\u30ea\u30fc\u30e0\u3067\u76ae\u819a\u3092\u4fdd\u8b77\u3059\u308b\u3053\u3068\u304c\u6cbb\u7642\u306e\u57fa\u672c\u3067\u3059\u3002 <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u30ea\u30c3\u30c1\u306a\u4fdd\u6e7f\u5264\u306f\u6bdb\u7a74\u3092\u585e\u3044\u3067\u30cb\u30ad\u30d3\u3092\u60aa\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u3053\u306e\u85ac\u304c\u89e3\u6c7a\u7b56\u306b\u306a\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u3053\u306e\u85ac\u306f\u9577\u671f\u4f7f\u7528\u306b\u3088\u308a\u76ae\u819a\u30d0\u30ea\u30a2\u3092\u5f37\u5316\u3057\u3066\u304f\u308c\u307e\u3059\u3002 <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d4c\u53e3\u30ec\u30c1\u30ce\u30a4\u30c9\u3082\u540c\u69d8\u306e\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u5507\u3084\u76ee\u306a\u3069\u5168\u8eab\u304c\u4e7e\u71e5\u3059\u308b\u526f\u4f5c\u7528\u304c\u73fe\u308c\u308b\u3053\u3068\u304c\u3042\u308b\u305f\u3081\u3001\u9577\u671f\u4f7f\u7528\u306b\u306f\u5916\u7528\u30ec\u30c1\u30ce\u30a4\u30c9\u306e\u65b9\u304c\u9069\u3057\u3066\u3044\u307e\u3059\u3002<sup><a style=\"color: inherit\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29974453\/\" target=\"_blank\" rel=\"noopener\">2<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 id=\"sec-3\" class=\"wp-block-heading\">3. \u30cb\u30ad\u30d3\u304c\u3067\u304d\u308b\u904e\u7a0b<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-color-5-color has-alpha-channel-opacity has-custom-color-5-background-color has-background is-style-wide\" style=\"margin-top:var(--wp--preset--spacing--superbspacing-xsmall);margin-bottom:var(--wp--preset--spacing--superbspacing-xsmall)\" \/>\n\n\n\n<p class=\"wp-block-paragraph\">\u30cb\u30ad\u30d3\u306f\u89d2\u8cea\u3068\u76ae\u8102\u304c\u6bdb\u7a74\u3092\u585e\u3050\u3053\u3068\u3067\u767a\u751f\u3057\u307e\u3059\u304c\u3001\u30a2\u30af\u30ea\u30fc\u30d5\u306f\u904e\u5270\u306a\u89d2\u8cea\u3068\u76ae\u8102\u306e\u751f\u6210\u3092\u6291\u5236\u3057\u307e\u3059\uff08\u8a73\u7d30\u306f<a href=\"https:\/\/miragen.clinic\/ja\/%e3%83%8b%e3%82%ad%e3%83%93\/\" data-type=\"page\" data-id=\"7210\">\u30cb\u30ad\u30d3<\/a>\u306e\u30da\u30fc\u30b8\u3092\u3054\u53c2\u7167\u304f\u3060\u3055\u3044\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u30ea\u30c3\u30c1\u306a\u4fdd\u6e7f\u5264\u3092\u4f7f\u7528\u3057\u306a\u304c\u3089\u3082\u3001\u6bdb\u7a74\u304c\u8a70\u307e\u3063\u3066\u30cb\u30ad\u30d3\u304c\u60aa\u5316\u3059\u308b\u306e\u3092\u7de9\u548c\u3067\u304d\u307e\u3059\u3002\u5fc5\u8981\u6027\u306f<a href=\"https:\/\/miragen.clinic\/ja\/%e3%82%a6%e3%83%83%e3%83%89%e7%81%af%e6%a4%9c%e6%9f%bb\/\">\u30a6\u30c3\u30c9\u706f\u691c\u67fb<\/a>\u3067\u6bdb\u7a74\u306e\u8a70\u307e\u308a\u5177\u5408\u3092\u898b\u3066\u5224\u65ad\u3057\u307e\u3059\u3002 <\/p>\n\n\n\n<figure class=\"wp-block-image alignwide size-large\"><img decoding=\"async\" width=\"1024\" height=\"765\" src=\"https:\/\/miragen.clinic\/wp-content\/uploads\/2026\/03\/wood-lamp-sebum-fluorescence-1.webp\" alt=\"\u30a6\u30c3\u30c9\u706f\u691c\u67fb\u3067\u982c\u3068\u9f3b\u306e\u5468\u308a\u306e\u76ae\u8102\u306e\u86cd\u5149\u53cd\u5fdc\u304c\u30d4\u30f3\u30af\u8272\u306e\u70b9\u3068\u3057\u3066\u73fe\u308c\u305f\u81e8\u5e8a\u5199\u771f \u2014 \u30a2\u30af\u30ea\u30fc\u30d5\u306e\u4f7f\u7528\u53ef\u5426\u3092\u5224\u65ad\u3059\u308b\u305f\u3081\u306b\u6d3b\u7528\" class=\"wp-image-6578\" title=\"\u30a6\u30c3\u30c9\u706f\u691c\u67fb \u2014 \u76ae\u8102\u306e\u86cd\u5149\u53cd\u5fdc\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 id=\"sec-4\" class=\"wp-block-heading\">4. \u524d\u4e16\u4ee3\u3088\u308a\u3082\u523a\u6fc0\u304c\u5c11\u306a\u3044\u3067\u3059<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-color-5-color has-alpha-channel-opacity has-custom-color-5-background-color has-background is-style-wide\" style=\"margin-top:var(--wp--preset--spacing--superbspacing-xsmall);margin-bottom:var(--wp--preset--spacing--superbspacing-xsmall)\" \/>\n\n\n\n<p class=\"wp-block-paragraph\">\u30ec\u30c1\u30ce\u30a4\u30c9\u306f\u89d2\u8cea\u7d30\u80de\u306e\u5bff\u547d\u3092\u5ef6\u3070\u3057\u307e\u3059\u3002\u7d30\u80de\u304c\u3088\u308a\u9577\u304f\u751f\u304d\u3066\u3044\u308b\u5206\u3001\u89d2\u8cea\u5c64\u3092\u69cb\u6210\u3059\u308b\u6b7b\u3093\u3060\u7d30\u80de\u304c\u6e1b\u308a\u3001\u6b7b\u3093\u3060\u7d30\u80de\u9593\u306e\u63a5\u7740\u529b\u3082\u5f31\u307e\u308a\u307e\u3059\u3002<sup><a style=\"color:inherit\" href=\"#\ucc38\uace0\ubb38\ud5cc\">3<\/a><\/sup> \u305d\u306e\u7d50\u679c\u3001\u4f7f\u7528\u521d\u671f\u306b<strong>\u76ae\u819a\u30d0\u30ea\u30a2\u304c\u4e00\u6642\u7684\u306b\u5f31\u304f\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/strong> <\/p>\n\n\n\n<figure class=\"wp-block-image alignwide size-full\"><img decoding=\"async\" width=\"1024\" height=\"844\" src=\"https:\/\/miragen.clinic\/wp-content\/uploads\/2026\/03\/retinoid-skin-layer-stratum-corneum-comparison.jpg\" alt=\"\u6b63\u5e38\u306a\u76ae\u819a\u3068\u30a2\u30af\u30ea\u30fc\u30d5\u9069\u7528\u5f8c\u306e\u8868\u76ae\u5c64\u306e\u6bd4\u8f03\u30a4\u30e9\u30b9\u30c8 \u2014 \u89d2\u8cea\u7d30\u80de\u306e\u5bff\u547d\u304c\u5ef6\u3073\u308b\u3053\u3068\u3067\u3001\u521d\u671f\u306b\u89d2\u8cea\u5c64\u304c\u8584\u304f\u306a\u308a\u3001\u76ae\u819a\u30d0\u30ea\u30a2\u304c\u4e00\u6642\u7684\u306b\u5f31\u304f\u306a\u308b\u904e\u7a0b\" class=\"wp-image-7071\" title=\"\u30ec\u30c1\u30ce\u30a4\u30c9\u4f7f\u7528\u5f8c\u306e\u89d2\u8cea\u5c64\u306e\u5909\u5316\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u7d4c\u9a13\u4e0a\u3001\u30a2\u30af\u30ea\u30fc\u30d5\u306f\u524d\u4e16\u4ee3\u306e\u30ec\u30c1\u30ce\u30a4\u30c9\u306b\u6bd4\u3079\u3066\u3053\u306e\u3088\u3046\u306a\u523a\u6fc0\u304c\u5c11\u306a\u304f\u89b3\u5bdf\u3055\u308c\u307e\u3059\u3002\u524d\u4e16\u4ee3\u306e\u30ec\u30c1\u30ce\u30a4\u30c9\u306fRAR-\u03b1\u30fb\u03b2\u30fb\u03b3\u3092\u540c\u6642\u306b\u523a\u6fc0\u3057\u307e\u3059\u304c\u3001\u3053\u306e\u85ac\u306f<strong>RAR-\u03b3\u306b\u306e\u307f\u9078\u629e\u7684\u306b\u7d50\u5408<\/strong>\u3059\u308b\u305f\u3081\u3060\u3068\u63a8\u6e2c\u3055\u308c\u307e\u3059\u3002<sup><a style=\"color:inherit\" href=\"#\ucc38\uace0\ubb38\ud5cc\">4<\/a><\/sup> <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 id=\"sec-5\" class=\"wp-block-heading\">5. \u7d4c\u53e3\u30ec\u30c1\u30ce\u30a4\u30c9\u3092\u5148\u306b\u4f7f\u3046\u7406\u7531<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-color-5-color has-alpha-channel-opacity has-custom-color-5-background-color has-background is-style-wide\" style=\"margin-top:var(--wp--preset--spacing--superbspacing-xsmall);margin-bottom:var(--wp--preset--spacing--superbspacing-xsmall)\" \/>\n\n\n\n<p class=\"wp-block-paragraph\">\u591a\u304f\u306e\u5834\u5408\u3001\u7d4c\u53e3\u30ec\u30c1\u30ce\u30a4\u30c9\u3092\u5148\u306b\u4f7f\u7528\u3057\u3066\u304b\u3089\u30a2\u30af\u30ea\u30fc\u30d5\u3092\u4f7f\u7528\u3059\u308b\u65b9\u304c\u3001\u6700\u521d\u304b\u3089\u30a2\u30af\u30ea\u30fc\u30d5\u3092\u4f7f\u7528\u3059\u308b\u3088\u308a\u3082\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d4c\u53e3\u30ec\u30c1\u30ce\u30a4\u30c9\u3067<strong>\u6bdb\u7a74\u3092\u958b\u3044\u3066<\/strong>\u304b\u3089\u30a2\u30af\u30ea\u30fc\u30d5\u3092\u4f7f\u7528\u3059\u308b\u3068\u3001\u85ac\u5264\u304c\u6bdb\u7a74\u306e\u5965\u307e\u3067\u5c4a\u304d\u3084\u3059\u304f\u306a\u308b\u305f\u3081\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d4c\u53e3\u30ec\u30c1\u30ce\u30a4\u30c9\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/miragen.clinic\/ja\/%e3%82%a4%e3%82%bd%e3%83%86%e3%82%a3%e3%83%8e%e3%83%b3\/\" data-type=\"page\" data-id=\"6421\">\u30a4\u30bd\u30c1\u30ce\u30f3<\/a>\u306e\u30da\u30fc\u30b8\u3067\u3054\u78ba\u8a8d\u3044\u305f\u3060\u3051\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 id=\"sec-6\" class=\"wp-block-heading\">6. \u4f7f\u7528\u65b9\u6cd5<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-color-5-color has-alpha-channel-opacity has-custom-color-5-background-color has-background is-style-wide\" style=\"margin-top:var(--wp--preset--spacing--superbspacing-xsmall);margin-bottom:var(--wp--preset--spacing--superbspacing-xsmall)\" \/>\n\n\n\n<p class=\"wp-block-paragraph\">\u524d\u4e16\u4ee3\u306b\u6bd4\u3079\u3066\u523a\u6fc0\u304c\u5c11\u306a\u3044\u3068\u306f\u3044\u3048\u3001\u30a2\u30af\u30ea\u30fc\u30d5\u3082\u30ec\u30c1\u30ce\u30a4\u30c9\u3067\u3042\u308b\u305f\u3081\u3001\u4fdd\u5b88\u7684\u306b\u958b\u59cb\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list has-custom-color-5-color has-text-color has-link-color wp-elements-1766579ad5cb057e74bb8fc428945c7f\">\n<li>\u30a2\u30af\u30ea\u30fc\u30d5\u3092<strong>\u722a\u306e\u534a\u5206<\/strong>\u307b\u3069\u306e\u91cf\u3001\u4fdd\u6e7f\u5264\u3068\u6df7\u305c\u305f\u5f8c\u3001\u76ee\u306e\u5468\u308a\u3092\u907f\u3051\u3066\u9854\u5168\u4f53\u306b\u8584\u304f\u4f38\u3070\u3057\u3066\u5857\u308a\u307e\u3059\u3002\u4fdd\u6e7f\u5264\u3068\u6df7\u305c\u306a\u3051\u308c\u3070\u9854\u5168\u4f53\u306b\u5857\u308c\u306a\u3044\u307b\u3069\u306e\u5c11\u91cf\u304b\u3089\u59cb\u3081\u3066\u304f\u3060\u3055\u3044\u3002 <\/li>\n\n\n\n<li>\u6700\u521d\u306e2\u9031\u9593\u306f<strong>3\u65e5\u306b1\u56de<\/strong>\u3060\u3051\u5857\u308a\u3001\u76ae\u819a\u306e\u53cd\u5fdc\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li>\u4f7f\u7528\u5f8c\u306b\u76ae\u819a\u304c\u8d64\u304f\u306a\u3063\u305f\u308a\u3001\u76ae\u819a\u708e\u304c\u518d\u767a\u3057\u305f\u308a\u3057\u305f\u5834\u5408\u306f\u3001\u4f7f\u7528\u91cf\u3068\u983b\u5ea6\u3092\u6e1b\u3089\u3059\u304b\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u5b8c\u5168\u306b\u4e2d\u6b62\u3057\u307e\u3059\u3002\u9006\u306b\u526f\u4f5c\u7528\u304c\u306a\u3051\u308c\u3070\u3001\u4f7f\u7528\u91cf\u3084\u983b\u5ea6\u3092\u6bb5\u968e\u7684\u306b\u5897\u3084\u3057\u307e\u3059\u3002 <\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 id=\"sec-7\" class=\"wp-block-heading\">7. \u598a\u5a20\u30fb\u6388\u4e73<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-color-5-color has-alpha-channel-opacity has-custom-color-5-background-color has-background is-style-wide\" style=\"margin-top:var(--wp--preset--spacing--superbspacing-xsmall);margin-bottom:var(--wp--preset--spacing--superbspacing-xsmall)\" \/>\n\n\n\n<p class=\"wp-block-paragraph\">\u30a2\u30af\u30ea\u30fc\u30d5\u306f\u30ec\u30c1\u30ce\u30a4\u30c9\u7cfb\u306e\u85ac\u5264\u3067\u3042\u308b\u305f\u3081\u3001<strong>\u598a\u5a20\u4e2d\u306f\u4f7f\u7528\u3067\u304d\u307e\u305b\u3093<\/strong>\u3002\u5c40\u6240\u5857\u5e03\u6642\u306e\u5168\u8eab\u5438\u53ce\u306f\u975e\u5e38\u306b\u4f4e\u3044\u3067\u3059\u304c\u3001\u305d\u308c\u3067\u3082\u598a\u5a20\u4e2d\u306e\u4f7f\u7528\u306f\u7981\u5fcc\u3067\u3059\u3002\u4f7f\u7528\u4e2d\u306b\u598a\u5a20\u304c\u5224\u660e\u3057\u305f\u5834\u5408\u306f\u3001\u76f4\u3061\u306b\u4f7f\u7528\u3092\u4e2d\u6b62\u3057\u3066\u304f\u3060\u3055\u3044\u3002  <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u6388\u4e73\u4e2d\u3082\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/strong> \u5c40\u6240\u5857\u5e03\u3057\u305f\u85ac\u5264\u304c\u6bcd\u4e73\u306b\u79fb\u884c\u3059\u308b\u304b\u3069\u3046\u304b\u306f\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u6388\u4e73\u4e2d\u306b\u4f7f\u7528\u304c\u5fc5\u8981\u306a\u5834\u5408\u306f\u3001\u6700\u5c0f\u9650\u306e\u9762\u7a4d\u306b\u77ed\u671f\u9593\u4f7f\u7528\u3057\u3001\u4e73\u982d\u3084\u4e73\u8f2a\u90e8\u4f4d\u306b\u306f\u5857\u3089\u306a\u3044\u3088\u3046\u306b\u3057\u3066\u304f\u3060\u3055\u3044\u3002 <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 id=\"sec-8\" class=\"wp-block-heading\">8. \u7d50\u8ad6<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-color-5-color has-alpha-channel-opacity has-custom-color-5-background-color has-background is-style-wide\" style=\"margin-top:var(--wp--preset--spacing--superbspacing-xsmall);margin-bottom:var(--wp--preset--spacing--superbspacing-xsmall)\" \/>\n\n\n\n<p class=\"wp-block-paragraph\">\u76ae\u819a\u708e\u306e\u60a3\u8005\u69d8\u306b\u3068\u3063\u3066\u3001\u30ea\u30c3\u30c1\u306a\u4fdd\u6e7f\u5264\u306f\u30d0\u30ea\u30a2\u4fdd\u8b77\u306b\u5927\u304d\u304f\u5f79\u7acb\u3061\u307e\u3059\u304c\u3001\u6bdb\u7a74\u3092\u585e\u3044\u3067\u30cb\u30ad\u30d3\u3092\u8a98\u767a\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u30a2\u30af\u30ea\u30fc\u30d5\u306f\u6bdb\u7a74\u306e\u9589\u585e\u3092\u4e88\u9632\u3057\u306a\u304c\u3089\u3001\u9577\u671f\u7684\u306b\u306f\u76ae\u819a\u30d0\u30ea\u30a2\u307e\u3067\u5f37\u5316\u3057\u3001\u3053\u306e\u30b8\u30ec\u30f3\u30de\u306b\u5bfe\u3059\u308b\u89e3\u6c7a\u7b56\u3068\u306a\u308a\u307e\u3059\u3002 <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6bdb\u7a74\u304c\u3072\u3069\u304f\u8a70\u307e\u3063\u3066\u3044\u308b\u5834\u5408\u306f\u3001<a href=\"https:\/\/miragen.clinic\/ja\/%e3%82%a4%e3%82%bd%e3%83%86%e3%82%a3%e3%83%8e%e3%83%b3\/\">\u30a4\u30bd\u30c1\u30ce\u30f3<\/a>\u3067\u5148\u306b\u6bdb\u7a74\u3092\u304d\u308c\u3044\u306b\u3057\u3066\u304b\u3089\u958b\u59cb\u3059\u308b\u306e\u304c\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-dots\" \/>\n\n\n\n<h3 id=\"\ucc38\uace0\ubb38\ud5cc\" class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h3>\n\n\n\n<ol class=\"wp-block-list has-custom-color-5-color has-text-color has-link-color has-superbfont-xxsmall-font-size wp-elements-50df961f5905fa7121302881ff50d7a6\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29706423\/\" target=\"_blank\" rel=\"noopener\"><em>Thoreau E, Arellano C, Jourdan F, et al. Structure-based design of Trifarotene (CD5789), a potent and selective RAR\u03b3 agonist for the treatment of acne. Bioorg Med Chem Lett. 2018;28(10):1736-1741.   <\/em><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29974453\/\" target=\"_blank\" rel=\"noopener\"><em>Aubert J, Piwnica D, Bertino B, et al. Nonclinical and human pharmacology of the potent and selective topical retinoic acid receptor-\u03b3 agonist trifarotene. Br J Dermatol. 2018;179(2):442-456.   <\/em><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22148010\/\" target=\"_blank\" rel=\"noopener\"><em>Yoon J, Bhatt LR, Yoo HJ, et al. Retinoid Induces the Degradation of Corneodesmosomes and Downregulation of Corneodesmosomal Cadherins: Implications on the Mechanism of Retinoid-induced Desquamation. Korean J Invest Dermatol. 2011;18(3):112-118.   <\/em><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34354358\/\" target=\"_blank\" rel=\"noopener\"><em>Sadeghian A, Markowski T, Engstrom KG, et al. Assessing the Safety and Efficacy of Trifarotene in the Treatment of Acne Vulgaris. Ther Clin Risk Manag. 2021;17:741-756.   <\/em><\/a><\/li>\n<\/ol>\n<\/div>\n\n<div class=\"wp-block-group has-custom-color-6-background-color has-background has-global-padding is-layout-constrained wp-container-core-group-is-layout-4c3b03bf wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--superbspacing-xlarge);padding-right:var(--wp--preset--spacing--superbspacing-small);padding-bottom:var(--wp--preset--spacing--superbspacing-xlarge);padding-left:var(--wp--preset--spacing--superbspacing-small)\">\n<h2 id=\"sec-faq\" class=\"wp-block-heading\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-color-5-color has-alpha-channel-opacity has-custom-color-5-background-color has-background is-style-wide\" style=\"margin-top:var(--wp--preset--spacing--superbspacing-xsmall);margin-bottom:var(--wp--preset--spacing--superbspacing-xsmall)\" \/>\n\n\n<div id=\"rank-math-faq\" class=\"rank-math-block\">\n<div class=\"rank-math-list \">\n<div id=\"faq-6422-001\" class=\"rank-math-list-item\">\n<h3 class=\"rank-math-question \">\u30a4\u30bd\u30c1\u30ce\u30f3\u306a\u3057\u3067\u30a2\u30af\u30ea\u30fc\u30d5\u3060\u3051\u4f7f\u3063\u3066\u3082\u3044\u3044\u3067\u3059\u304b\uff1f<\/h3>\n<div class=\"rank-math-answer \">\n\n<p>\u53ef\u80fd\u3067\u3059\u3002\u305f\u3060\u3057\u3001\u6bdb\u7a74\u304c\u3059\u3067\u306b\u3072\u3069\u304f\u8a70\u307e\u3063\u3066\u3044\u308b\u3068\u3001\u85ac\u5264\u304c\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u5341\u5206\u306b\u5230\u9054\u3057\u306b\u304f\u304f\u306a\u308a\u307e\u3059\u3002\u6bdb\u7a74\u306e\u72b6\u614b\u306b\u5fdc\u3058\u3066\u3001\u30a4\u30bd\u30c1\u30ce\u30f3\u3092\u5148\u306b\u4f7f\u3046\u3079\u304d\u304b\u5224\u65ad\u3057\u307e\u3059\u3002  <\/p>\n\n<\/div>\n<\/div>\n<div id=\"faq-6422-002\" class=\"rank-math-list-item\">\n<h3 class=\"rank-math-question \">\u4fdd\u6e7f\u5264\u306a\u3057\u3067\u30a2\u30af\u30ea\u30fc\u30d5\u3060\u3051\u5857\u3063\u3066\u3082\u3044\u3044\u3067\u3059\u304b\uff1f<\/h3>\n<div class=\"rank-math-answer \">\n\n<p>\u63a8\u5968\u3057\u307e\u305b\u3093\u3002\u30a2\u30af\u30ea\u30fc\u30d5\u306f\u3054\u304f\u5c11\u91cf\uff08\u722a\u306e\u534a\u5206\uff09\u3057\u304b\u4f7f\u7528\u3057\u306a\u3044\u305f\u3081\u3001\u4fdd\u6e7f\u5264\u3068\u6df7\u305c\u308b\u3053\u3068\u3067\u9854\u5168\u4f53\u306b\u5747\u4e00\u306b\u5857\u5e03\u3067\u304d\u307e\u3059\u3002\u4fdd\u6e7f\u5264\u306f\u30ec\u30c1\u30ce\u30a4\u30c9\u306b\u3088\u308b\u523a\u6fc0\u3082\u8efd\u6e1b\u3057\u3066\u304f\u308c\u308b\u305f\u3081\u3001\u4f75\u7528\u3059\u308b\u3053\u3068\u3092\u304a\u52e7\u3081\u3057\u307e\u3059\u3002  <\/p>\n\n<\/div>\n<\/div>\n<div id=\"faq-6422-003\" class=\"rank-math-list-item\">\n<h3 class=\"rank-math-question \">\u5857\u3063\u305f\u3089\u9854\u304c\u8d64\u304f\u306a\u308a\u3001\u76ae\u819a\u708e\u304c\u518d\u767a\u3057\u307e\u3057\u305f\u3002<\/h3>\n<div class=\"rank-math-answer \">\n\n<p>\u4f7f\u7528\u91cf\u3068\u983b\u5ea6\u3092\u6e1b\u3089\u3059\u304b\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u5b8c\u5168\u306b\u4e2d\u6b62\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u76ae\u819a\u306e\u72b6\u614b\u304c\u5b89\u5b9a\u3057\u305f\u5f8c\u3001\u3088\u308a\u5c11\u306a\u3044\u91cf\u3067\u518d\u8a66\u884c\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 <\/p>\n\n<\/div>\n<\/div>\n<div id=\"faq-6422-004\" class=\"rank-math-list-item\">\n<h3 class=\"rank-math-question \">\u30c7\u30a3\u30d5\u30a7\u30ea\u30f3\u3068\u306f\u4f55\u304c\u9055\u3046\u306e\u3067\u3059\u304b\uff1f<\/h3>\n<div class=\"rank-math-answer \">\n\n<p>\u30c7\u30a3\u30d5\u30a7\u30ea\u30f3\uff08\u30a2\u30c0\u30d1\u30ec\u30f3\uff09\u306f\u7b2c3\u4e16\u4ee3\u3001\u30a2\u30af\u30ea\u30fc\u30d5\uff08\u30c8\u30ea\u30d5\u30a1\u30ed\u30c6\u30f3\uff09\u306f\u7b2c4\u4e16\u4ee3\u306e\u30ec\u30c1\u30ce\u30a4\u30c9\u3067\u3059\u3002\u81e8\u5e8a\u7684\u306b\u30a2\u30af\u30ea\u30fc\u30d5\u306e\u65b9\u304c\u76ae\u819a\u523a\u6fc0\u304c\u5c11\u306a\u304f\u89b3\u5bdf\u3055\u308c\u3001\u5168\u8eab\u5438\u53ce\u304c\u4f4e\u3044\u305f\u3081\u3001\u5e83\u7bc4\u56f2\u306b\u3082\u9069\u7528\u3067\u304d\u307e\u3059\u3002 <\/p>\n\n<\/div>\n<\/div>\n<div id=\"faq-6422-005\" class=\"rank-math-list-item\">\n<h3 class=\"rank-math-question \">\u663c\u9593\u306b\u5857\u3063\u3066\u3082\u3044\u3044\u3067\u3059\u304b\uff1f<\/h3>\n<div class=\"rank-math-answer \">\n\n<p>\u30a2\u30af\u30ea\u30fc\u30d5\u306f\u591c\u306b\u5857\u308a\u307e\u3059\u3002\u4f7f\u7528\u4e2d\u306f\u89d2\u8cea\u5c64\u304c\u8584\u304f\u306a\u308a\u3001\u76ae\u819a\u304c\u7d2b\u5916\u7dda\u306b\u5bfe\u3057\u3066\u3088\u308a\u8106\u5f31\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u4e0d\u8981\u306a\u65e5\u5149\u3078\u306e\u9732\u51fa\u306f\u907f\u3051\u308b\u306e\u304c\u671b\u307e\u3057\u3044\u3067\u3059\u3002 <\/p>\n\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u85ac\u5264\u6848\u5185 \u30a2\u30af\u30ea\u30fc\u30d5 | \u76ae\u819a\u30d0\u30ea\u30a2\u3068\u76ae\u8102\u3001\u4e8c\u514e\u3092\u8ffd\u3063\u3066\u4e8c\u514e\u3092\u5f97\u308b\u30af\u30ea\u30fc\u30e0 \u30a2\u30af\u30ea\u30fc\u30d5\u306f\u3001\u30cb\u30ad\u30d3\u6cbb\u7642\u306b\u4f7f\u7528\u3055\u308c\u308b\u5916\u7528\u30ec\u30c1\u30ce\u30a4\u30c9\u3067\u3059\u3002 \u30cb\u30ad\u30d3\u3092\u4f34\u3046\u76ae\u819a\u708e\u306e\u60a3\u8005\u69d8\u306b\u5bfe\u3057\u3001\u30cb\u30ad\u30d3\u6cbb\u7642\u3060\u3051\u3067\u306a\u304f\u3001\u30ea\u30c3\u30c1\u306a\u4fdd\u6e7f\u5264\u306e\u4f7f\u7528\u3092\u53ef\u80fd\u306b\u3059 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":13561,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-full-width","meta":{"_miragen_jsonld":"","footnotes":""},"class_list":["post-13560","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/miragen.clinic\/ja\/wp-json\/wp\/v2\/pages\/13560","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/miragen.clinic\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/miragen.clinic\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/miragen.clinic\/ja\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/miragen.clinic\/ja\/wp-json\/wp\/v2\/comments?post=13560"}],"version-history":[{"count":6,"href":"https:\/\/miragen.clinic\/ja\/wp-json\/wp\/v2\/pages\/13560\/revisions"}],"predecessor-version":[{"id":13635,"href":"https:\/\/miragen.clinic\/ja\/wp-json\/wp\/v2\/pages\/13560\/revisions\/13635"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/miragen.clinic\/ja\/wp-json\/wp\/v2\/media\/13561"}],"wp:attachment":[{"href":"https:\/\/miragen.clinic\/ja\/wp-json\/wp\/v2\/media?parent=13560"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}